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タイトル: Retrospective study of clinical and laboratory findings of autosomal recessive cholesterol deficiency in Holstein calves in Japan
著者: Inokuma, Hisashi
Horiuchi, Noriyuki
Watanabe, Ken-ichi
Kobayashi, Yoshiyasu
キーワード: autosomal recessive cholesterol deficiency
Holstein
retrospective study
発行日: May-2017
出版者: Hokkaido University
誌名: Japanese Journal of Veterinary Research
巻: 65
号: 2
開始ページ: 107
終了ページ: 112
抄録: This retrospective study was conducted to clarify the clinical findings of an autosomal recessive cholesterol deficiency disorder in Holstein calves. Thirty-three calves with poor growth by uncertain causes from 2007 to 2016 comprised the study population of calves that were homozygous (n = 12) and non-homozygous (n = 21) for the disease. No significant group-dependent differences were found in the proportion with diarrhea or fever. Fewer calves with ataxia and anorexia were found in homozygotes. All affected calves showed muscular atrophy. Median RBC, Hb, and Ht values in affected calves were significantly lower. Median total cholesterol (TC) in homozygotes was extremely low, at 6.5 mg/dl (range, 5.0-15.0). TC readings under 10 mg/dl were thought to be suggestive of the disease.
URI: http://ir.obihiro.ac.jp/dspace/handle/10322/4439
DOI: info:doi/10.14943/jjvr.65.2.107
ISSN: 0047-1917
出現コレクション:00B01学術雑誌論文

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