帯広畜産大学 学術情報リポジトリ >
000研究域 >
00A畜産衛生学研究部門 >
00A01学術雑誌論文 >

このアイテムの引用には次の識別子を使用してください: http://ir.obihiro.ac.jp/dspace/handle/10322/4325

タイトル: Molecular and cellular mechanisms for the regulation of ovarian follicular function in cows
著者: SHIMIZU, Takashi
清水, 隆
キーワード: Endotoxin
Metabolic factors
Ovarian follicle
Steroid hormone
Vascular endothelial growth factor (VEGF)
発行日: 2016
出版者: 日本繁殖生物学会
誌名: Journal of Reproduction and Development
巻: 62
号: 4
開始ページ: 323-329
抄録: Ovary is an important organ that houses the oocytes (reproductive cell). Oocyte growth depends on the function of follicular cells such as the granulosa and theca cells. Two-cell two gonadotropin systems are associated with oocyte growth and follicular cell functions. In addition to these systems, it is also known that several growth factors regulate oocyte growth and follicular cell functions. Vascular endothelial growth factor (VEGF) is involved in thecal vasculature during follicular development and the suppression of granulosa cell apoptosis. Metabolic factors such as insulin, growth hormone (GH) and insulin-like growth factor 1 (IGF-1) also play critical roles in the process of follicular development and growth. These factors are associated not only with follicular development, but also with follicular cell function. Steroid hormones (estrogens, androgens, and progestins) that are secreted from follicular cells influence the function of the female genital tract and its affect the susceptibility to bacterial infection. This review covers our current understanding of the mechanisms by which gonadotrophins and/or steroid hormones regulate the growth factors in the follicular cells of the bovine ovary. In addition, this review describes the effect of endotoxin on the function of follicular cells.
URI: http://ir.obihiro.ac.jp/dspace/handle/10322/4325
ISSN: 1348-4400
0916-8818
権利情報: 日本繁殖生物学会
出現コレクション:00A01学術雑誌論文

このアイテムのファイル:

ファイル 記述 サイズフォーマット
shimizu62(4),323-329,2016.pdf812 kBAdobe PDF見る/開く

このリポジトリに保管されているアイテムはすべて著作権により保護されています。

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2006 MIT and Hewlett-Packard - ご意見をお寄せください