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タイトル: Experimental investigation of bone mineral density in Thoroughbreds using quantitative computed tomography
著者: YAMADA, Kazutaka
SATO, Fumio
HIGUCHI, Tohru
NISHIHARA, Kaori
KAYANO, Mitsunori
SASAKI, Naoki
NAMBO, Yasuo
山田, 一孝
茅野, 光範
佐々木, 直樹
南保, 泰雄
キーワード: bone mineral density
dual energy X-ray absorptiometry
quantitative computed tomography
radiographic bone aluminum equivalence
Thoroughbred
発行日: 2015
出版者: 日本ウマ科学会
抄録: Bone mineral density (BMD) is one of the indications of the strength and health. BMD measured by quantitative computed tomography (QCT) was compared with that measured by dual energy X-ray absorptiometry (DXA) and radiographic bone aluminum equivalence (RBAE). Limbs were removed from horses that had been euthanized for reasons not associated with this study. Sixteen limbs (left and right metacarpals and metatarsals) from 4 horses were used to compare BMD as measured by QCT with those measured by DXA and RBAE. There was a strong correlation between BMD values measured by QCT and those measured by DXA (R2=0.85); correlation was also observed between values obtained by QCT and those obtained by RBAE (R2=0.61). To investigate changes in BMD with age, 37 right metacarpal bones, including 7 from horses euthanized because of fracture were examined by QCT. The BMD value of samples from horses dramatically increased until 2 years of age and then plateaued, a pattern similar to the growth curve. The BMD values of bone samples from horses euthanized because of fracture were within the population range, and samples of morbid fracture were not included. The relationship between BMD and age provides a reference for further quantitative studies of bone development and remodeling. Quantitative measurement of BMD using QCT may have great potential for the evaluation of bone biology for breeding and rearing management.
記述: This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License <http://creativecommons.org/licenses/by-nc-nd/3.0/>.
URI: http://ir.obihiro.ac.jp/dspace/handle/10322/4182
ISSN: 1347-7501
1340-3516
出現コレクション:00B01学術雑誌論文

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