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タイトル: Proliferative Enteropathy Involving Lawsonia intracellularis Infection in Rabbits (Oryctlagus cuniculus)
著者: HORIUCHI, Noriyuki
WATARAI, Masahisa
KOBAYASHI, Yoshiyasu
OMATA, Yoshitaka
FURUOKA, Hidefumi
堀内, 雅之
古林, 与志安
古岡, 秀文
キーワード: Lawsonia intracellularis
proliferative enteropathy
rabbit
発行日: 2008
出版者: 日本獣医学会
誌名: Journal of Veterinary Medical Science
巻: 70
号: 4
開始ページ: 389-392
抄録: Five rabbits suffering from diarrhea were diagnosed with proliferative enteropathy (PE). Histopathology revealed a thickened mucosa consisting of hyperplastic intestinal epithelium and infiltration of inflammatory cells mainly consisted of macrophages. In the affected epithelial cytoplasm, numerous curved bacillus-like organisms were observed in the Warthin-Starry silver stain and electron microscopy observation. In polymerase chain reactions, Lawsonia intracellularis-specific DNA fragment were amplified from affected ileal tissue extracted DNA in each case and present 5 cases were confirmed to be L. intracellularis infection. Serum collected from the affected rabbit was immunohistochemically reactive with L. intracellularis in tissue sections from pigs with porcine proliferative enteropathy, as well as with tissue sections from the five affected rabbits. Thus, serum obtained from the affected rabbit may be applicable to immunohistochemical detection for L. intracellularis infection in other species.
URI: http://ir.obihiro.ac.jp/dspace/handle/10322/4169
ISSN: 1347-7439
0916-7250
権利情報: 日本獣医学会
出現コレクション:00C01学術雑誌論文

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