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タイトル: Beneficial Effect of Hyperbaric Oxygen Therapy on the Follicular Survival in the Mouse Ovary after Transplantation
著者: HAYASHI, Satomi
ASANO, Tomoyoshi
KAKIZAKI, Ryujiro
SUZUKI, Hiroshi
鈴木, 宏志
キーワード: Hyperbaric oxygen
Mice
Ovary
Transplantation
発行日: 2012
出版者: 日本繁殖生物学会
誌名: Journal of Reproduction and Development
巻: 58
号: 2
開始ページ: 260-263
抄録: A large proportion of follicles are lost during the initial ischemia that occurs after transplantation of ovarian tissues. Thus, the effect of hyperbaric oxygen therapy (HBO) on the follicular loss of ovarian tissues after transplantation was examined in mice. Ovarian slices from ICR mice were transplanted under the kidney capsule in ovariectomized ICR. Hyperbaric oxygen with 100% oxygen was initiated for 30 min at 2.5 atmospheres absolute immediately after transplantation, and this treatment was repeated at 48-h intervals for 2 weeks. The number of follicles was dramatically reduced at 2 weeks post transplantation. However, HBO was significantly effective in enhancing the survival of transplanted ovarian follicles. The survival rates of primordial and primary follicles in ovarian tissues of mice with HBO were significantly higher than those without HBO. These results indicate HBO can be effectively used for the enhancement of survival of transplanted ovarian tissues.
URI: http://ir.obihiro.ac.jp/dspace/handle/10322/3857
ISSN: 1348-4400
0916-8818
権利情報: Reproduction and Development
出現コレクション:05001学術雑誌論文

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